William Saliba missed training after picking up a knock, so he joined Gabriel among the absentees. Hincapie is back in the team after playing in last weekend’s North London derby, looking to partner up with his fellow summer signing Mosquera.
Leandro Trossard is also unavailable after featuring in our midweek win, so Gabriel Martinelli has taken his place at left back, after making a goalscoring impact from the bench in the Champions League.
The other change is at left back, where Riccardo Calafiori replaces Miles Lewis-Skelley.
There is good news among the substitutes, with Gabriel Jesus returning to the matchday squad for the first time since playing against Manchester United in the FA Cup 322 days ago.
Victor Gyökeres is also back on the bench, having missed the last four matches due to a hamstring injury.
Chelsea are unbeaten in six matches, and come into the game fresh off a Champions League victory.
He made only one change to the team that beat Barcelona, bringing on Joao Pedro in place of Alejandro Garnacho.
Cole Palmer has joined the cast after recovering from a toe injury.
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Preview: Chelsea vs Arsenal
line ups
Arsenal: Raya, Timber, Mosquera, Hincapie, Calafiori, Rice, Zubimendi, Eze, Saka, Martinelli, Merino.
Sub: Arrizabalaga, Lewis-Skelley, White, Odegaard, Norgaard, Nwaneri, Madueke, Gyöckeres, Jesus.
Chelsea: Sanchez, Gusto, Fofana, Cucurella, Chalobah, James, Fernandez, Estevao, Caicedo, Pedro Neto, Pedro.
Sub: Jorgensen, Acheampong, Tosin, Badiashile, Santos, Palmer, Gittens, Garnacho, Delap.
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