Furphy drove towards the basket and dunked but while landing he hurt himself, immediately catching his right knee and falling to the floor.
The 21-year-old Melburnian was able to leave the court with the help of assistance before being taken to the locker room in a wheelchair.
Furphy, drafted at No. 35 overall in 2024, has made 34 appearances in his second season with Indiana, averaging 5.2 points, 4.4 rebounds, 1.1 assists and 18.5 minutes of court time per game.
The Pacers lost 122-104 in Toronto on Monday (AEDT), with the team providing an update on Furphy following further medical evaluation.
“We’re not sure about Furphy’s status,” Pacers coach Rick Carlisle told reporters after the game.
“He will be tested tomorrow in New York and we will see where things are.
“We’re hoping it’s not that bad but we don’t know yet. We’ll hope for the best.”
Earlier, Furphy opened the scoring for Indiana with a two-handed dunk off a pass from Jay Huff.
Furphy had four points, three assists and two rebounds in 15 minutes on the court before his injury.
Scotty Barnes had 25 points and 14 rebounds for the Raptors, who were also keyed by RJ Barrett (20 points) and Sandro Mamukelashvili (17).
Trayce Jackson-Davis had 10 points and 10 rebounds in 15 minutes in his Toronto debut after being traded from Golden State.
Pascal Siakam had 18 points for the Pacers, who have lost four straight games and are in last place in the Eastern Conference with a 13-40 record.
Furphy Johnny Furphy (R) in action at Toronto before his injury. (AP Photo) Elsewhere, Jalen Brunson scored 31 points and Josh Hart added 19 points to help New York end Boston’s five-game winning streak with a 111-89 victory.
Jaylen Brown (26 points) and Derrick White (19) were the leads for the Celtics, who shot just 37 percent from the field, including 7 of 41 from long range.
Boston entered the tournament one game ahead of New York, but the Knicks are now in second place in the Eastern Conference and both sides have 34–19 records.
Kawhi Leonard had 41 points and eight rebounds as the Los Angeles Clippers beat Minnesota 115–96.
Kasparas Zakousionis went 6 of 6 from three-point range and finished with 22 points as Miami beat Washington 132–101.
Meanwhile, the Wizards made injured guard Dante Exum the third Australian to be waived by an NBA team this season.
With the 30-year-old sidelined by a knee injury, Dallas recently made a deal that also moved 10-time All-Star Anthony Davis to Washington.
Exum will be a free agent next season.
Luke Travers (Cleveland) and Duop Reith (Atlanta) were also waived before the trade deadline.
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